comparison of epidemiological, clinical, laboratory and radiological features of hospitalized diabetic and non-diabetic patients with pulmonary tuberculosis at razi hospital in ahvaz

background diabetes mellitus (dm) due to suppressive effect on cellular immunity can impact on progression of tuberculosis (tb). objectives the aim of this study was to investigate the impact of dm on the epidemiological, clinical and para clinical aspects of pulmonary tb. patients and methods the information of 148 admitted pulmonary tb patients in infectious ward of razi hospital in ahvaz from 2009 to 2010 was extracted from their medical files. the patients were divided into two groups as tb with dm (n = 36) and tb without dm (n = 112). the related data on epidemiology, signs, symptoms, radiology and sputum smear examination in both groups were compared in spss 16 by using chi squared test. results the mean age of tb with dm patients was higher tb without dm patients (56.6 ± 12.7 vs. 44.8 ± 18.3; respectively, p = 0.006). whereas cough, night sweating, fever and weigh loss was not statistically different, sputum, hemoptysis and dyspnea was more prominent in tb with dm (69.4%, 33.4%, 44.5% vs. 36.6%, 9.8%, 20.5%; p = 0.005, p = 0.001, p = 0.005, respectively). in chest x-ray, cavitation and reticulonodular pattern was more frequent in tb with dm (55.5%, 22.2% vs. 31.2%, 8% - p = 0.008, p = 0.02, respectively). the rate of sputum smear positivity in tb with dm and tb without dm was 66.6% and 47.3%, respectively (p = 0.03). conclusions according to the results of this study, in approach to every dm cases suffering of respiratory symptoms such as productive cough, hemoptysis and dyspnea in association with cavitation or miliary mottling in chest x-ray, pulmonary tb should be considered at the top of the differential diagnosis list.